NAD+ 500mg
Availability: In stock
Product Description
NAD+ 500mg — Nicotinamide Adenine Dinucleotide Research Compound
NAD+ (nicotinamide adenine dinucleotide) is a dinucleotide coenzyme present in all living cells and a central mediator of energy metabolism, redox biology, and cellular signaling. It is an essential cofactor for hundreds of enzymatic reactions and a key research compound in cellular-aging and metabolism studies. Each vial contains 500mg at ≥98% purity, verified by HPLC.
Research Specifications
| Compound | NAD+ (beta-Nicotinamide Adenine Dinucleotide) |
| CAS Number | 53-84-9 |
| Molecular Formula | C21H27N7O14P2 |
| Molecular Weight | 663.4 g/mol |
| PubChem CID | 5892 |
| Purity | ≥98% (HPLC / MS verified) |
| Appearance | White to off-white powder |
| Solubility | Soluble in water and bacteriostatic water |
| Form | Lyophilized powder for reconstitution |
Mechanism of Action
NAD+ functions as an electron carrier in central metabolism, cycling between its oxidized (NAD+) and reduced (NADH) forms to drive redox reactions in glycolysis, the citric-acid cycle, and oxidative phosphorylation.
Sirtuin Signaling
Beyond its redox role, NAD+ is an obligate substrate for the sirtuin family of deacylases, linking cellular NAD+ availability to gene-regulation and DNA-repair signaling—a major focus of cellular-aging research (Covarrubias et al., 2021).
Age-Related NAD+ Decline
Research documents a decline in cellular NAD+ with age, making NAD+ and its precursors (NMN, NR) important tools for studying metabolic and aging pathways.
Research Applications
Cellular-Metabolism Research
A fundamental coenzyme for studying redox reactions and energy metabolism.
Sirtuin & DNA-Repair Signaling
Used to investigate NAD+-dependent sirtuin activity and cellular-aging pathways.
Metabolic-Aging Models
Studied alongside NAD+ precursors and related compounds such as the NNMT inhibitor 5-Amino-1MQ.
Published Research Studies
1. Covarrubias AJ, et al. (2021) – NAD+ metabolism in ageing
A comprehensive Nature Reviews article on NAD+ metabolism and its roles in cellular processes during ageing. (PMID: 33353981)
Reconstitution and Handling in Research
The following summarizes standard laboratory handling for lyophilized research peptides. This product is intended for research use only and is not for human consumption.
Gently swirl to dissolve—do not shake, as agitation can shear peptide structure. The solvent volume selected determines the working concentration for a given research protocol.
Storage and Handling
Lyophilized (unreconstituted): Store at -20°C for long-term stability (up to 24 months) or at 2–8°C for shorter periods, protected from light and moisture. Avoid repeated freeze-thaw cycles.
Reconstituted: Store at 2–8°C and use within 4–6 weeks. For longer storage, aliquot into single-use volumes and freeze at -20°C. See our full peptide storage guide.
Safety Profile in Research
As with all research compounds, investigators should follow standard laboratory safety protocols, including appropriate personal protective equipment (PPE) when handling reconstituted solutions. NAD+ 500mg is for in-vitro and laboratory research use only and is not intended for human consumption, therapeutic use, or diagnostic purposes. A downloadable Research Product Safety Sheet is available in the Documentation & Research Resources section on this page.
Frequently Asked Questions
What is NAD+ used for in research?
NAD+ is used to study cellular metabolism, redox biology, sirtuin signaling, and cellular-aging pathways in laboratory models. It is intended strictly for research use.
Why is NAD+ important in aging research?
NAD+ is a substrate for sirtuin enzymes and declines with age; researchers study it to investigate metabolic and DNA-repair signaling in cellular-aging models.
What is the purity of NAD+ 500mg?
Each batch is verified at ≥98% purity by HPLC.
Why Buy NAD+ 500mg from Iron Peak Peptides?
Every batch of NAD+ 500mg undergoes third-party analytical testing—HPLC, mass spectrometry, and endotoxin screening—to verify purity, identity, and composition, with batch-specific quality-assurance documentation included. Iron Peak Peptides maintains full traceability from raw material to finished vial, ships quickly with proper handling, and backs every order with responsive research support. When you choose IronPeak, you partner with a supplier that prioritizes scientific rigor and product quality above all else.
