GHRP-6 10mg
Availability: Only 20 left in stock
Product Description
GHRP-6 10mg — Growth Hormone Releasing Hexapeptide
GHRP-6 was one of the first synthetic growth hormone-releasing peptides developed and remains a foundational research tool for the ghrelin/GHS-R1a receptor system. It is notable in the literature for its pronounced stimulation of appetite signaling alongside GH release, making it a distinctive probe for energy-balance research. Each vial contains 10mg of lyophilized peptide at ≥98% purity, verified by HPLC and mass spectrometry.
Research Specifications
| Compound | GHRP-6 (Growth Hormone Releasing Peptide-6) |
| CAS Number | 87616-84-0 |
| Molecular Formula | C46H56N12O6 |
| Molecular Weight | 873.0 g/mol |
| PubChem CID | 6918245 |
| Sequence | His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 (hexapeptide) |
| Reported Half-Life | ~15–30 minutes (short-acting) in published reports |
| Purity | ≥98% (HPLC / MS verified) |
| Appearance | White lyophilized powder |
| Solubility | Soluble in bacteriostatic or sterile water |
| Form | Lyophilized powder for reconstitution |
Mechanism of Action
GHRP-6 is a synthetic hexapeptide agonist of the growth hormone secretagogue receptor (GHS-R1a). Binding activates phospholipase-C signaling in pituitary somatotrophs, elevating intracellular calcium and stimulating GH release independently of the GHRH pathway.
Appetite-Signaling Probe
Among the GHRPs, GHRP-6 is particularly associated in published research with robust activation of central ghrelin-receptor pathways linked to appetite and food-seeking behavior, making it a widely cited tool for hunger-signaling investigations.
Complementary to GHRH
Because it engages a different receptor than GHRH analogs, GHRP-6 is frequently studied in combination with GHRH-class peptides to examine additive or synergistic secretagogue effects on the somatotropic axis.
Research Applications
GH Secretagogue Research
Used to study somatotroph activation and GH pulse generation in preclinical endocrine models.
Ghrelin & Appetite Signaling
GHRP-6's strong GHS-R1a agonism makes it a reference compound for research into appetite regulation and energy homeostasis.
Structure-Activity Comparisons
Investigators compare GHRP-6 with GHRP-2 and hexarelin to characterize potency, selectivity, and receptor kinetics across the GHRP family.
Published Research Studies
1. Bowers CY, et al. (1984) – discovery of GH-releasing peptides
Described the original synthetic GHRP compounds, including the GHRP-6 pharmacophore, establishing the GHS receptor concept. (PMID: 6543048)
Reconstitution and Handling in Research
The following summarizes standard laboratory handling for lyophilized research peptides. This product is intended for research use only and is not for human consumption.
Reconstitute the lyophilized powder by adding bacteriostatic or sterile water down the inside wall of the vial using a sterile syringe. Gently swirl to dissolve—do not shake, as agitation can shear peptide structure. The solvent volume selected determines the working concentration for a given research protocol. For step-by-step technique and dilution calculations, see our peptide reconstitution guide and pair with bacteriostatic water.
Storage and Handling
Lyophilized (unreconstituted): Store at -20°C for long-term stability (up to 24 months) or at 2–8°C for shorter periods, protected from light and moisture. Avoid repeated freeze-thaw cycles.
Reconstituted: Store at 2–8°C and use within 4–6 weeks. For longer storage, aliquot into single-use volumes and freeze at -20°C. See our full peptide storage guide.
Safety Profile in Research
As with all research compounds, investigators should follow standard laboratory safety protocols, including appropriate personal protective equipment (PPE) when handling reconstituted solutions. GHRP-6 10mg is for in-vitro and laboratory research use only and is not intended for human consumption, therapeutic use, or diagnostic purposes. A downloadable Research Product Safety Sheet is available in the Documentation & Research Resources section on this page.
Frequently Asked Questions
What is GHRP-6 used for in research?
GHRP-6 is used in laboratory research to study GHS-R1a receptor signaling, GH release, and ghrelin-mediated appetite pathways. It is intended strictly for research use.
How does GHRP-6 differ from GHRP-2?
Both are GHS-R1a agonists, but published research associates GHRP-6 with stronger appetite-signaling effects, while GHRP-2 is generally reported as a more potent GH secretagogue. They are commonly studied comparatively.
What is the purity of GHRP-6 10mg?
Each batch is verified at ≥98% purity by HPLC and mass spectrometry, with batch-specific documentation.
Why Buy GHRP-6 10mg from Iron Peak Peptides?
Every batch of GHRP-6 10mg undergoes third-party analytical testing—HPLC, mass spectrometry, and endotoxin screening—to verify purity, identity, and composition, with batch-specific quality-assurance documentation included. Iron Peak Peptides maintains full traceability from raw material to finished vial, ships quickly with proper handling, and backs every order with responsive research support. When you choose IronPeak, you partner with a supplier that prioritizes scientific rigor and product quality above all else.
